A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

580

Participants

Timeline

Start Date

December 14, 2022

Primary Completion Date

March 6, 2025

Study Completion Date

June 29, 2029

Conditions
Cardiomyopathy, Hypertrophic
Interventions
DRUG

Mavacamten

Specified dose on specified days

OTHER

Placebo

Specified dose on specified days

Trial Locations (224)

0

Local Institution - 0508, Seongnam-si

1070

Local Institution - 0034, Anderlecht

1090

Local Institution - 0429, Vienna

1096

Local Institution - 0048, Budapest

1097

Local Institution - 0039, Budapest

1122

Local Institution - 0035, Budapest

1478

Local Institution - 0443, Lørenskog

2010

Local Institution - 0085, Darlinghurst

2139

Local Institution - 0063, Concord

2170

Local Institution - 0369, Sydney

2650

Local Institution - 0462, Edegem

3000

Local Institution - 0319, Leuven

3600

Local Institution - 0476, Genk

4020

Local Institution - 0075, Linz

4032

Local Institution - 0080, Chermside

4064

Local Institution - 0078, Milton

5042

Local Institution - 0050, Bedford Park

5280

Local Institution - 0069, Braunau am Inn

6020

Local Institution - 0090, Innsbruck

6150

Local Institution - 0076, Murdoch

6200

Local Institution - 0428, Aabenraa

6351

Local Institution - 0055, Seoul

6591

Local Institution - 0460, Seoul

6720

Local Institution - 0417, Szeged

7030

Local Institution - 0473, Trondheim

8036

Local Institution - 0062, Graz

8200

Local Institution - 0019, Aarhus N

8230

Local Institution - 0423, Balatonfüred

10595

Local Institution - 0426, Valhalla

13100

Local Institution - 0253, Safed

13353

Local Institution - 0403, Berlin

15006

Local Institution - 0043, A Coruña

17033

Local Institution - 0047, Hershey

18014

Local Institution - 0060, Granada

19104

Local Institution - 0263, Philadelphia

20246

Local Institution - 0032, Hamburg

21287

Local Institution - 0127, Baltimore

22332

Local Institution - 0518, Incheon

23538

Local Institution - 0066, Lübeck

27710

Local Institution - 0065, Durham

28034

Local Institution - 0421, Madrid

28222

Local Institution - 0021, Majadahonda

29010

Local Institution - 0041, Málaga

29200

Local Institution - 0463, Brest

30120

Local Institution - 0237, El Palmar

30322

Local Institution - 0092, Atlanta

30625

Local Institution - 0448, Hanover

31400

Local Institution - 0005, Toulouse

32545

Local Institution - 0439, Bad Oeynhausen

33604

Local Institution - 0053, Pessac

Local Institution - 0174, Bielefeld

35000

Local Institution - 0008, Rennes

37007

Local Institution - 0031, Salamanca

37044

Local Institution - 0003, Chambray-lès-Tours

37075

Local Institution - 0496, Göttingen

38700

Local Institution - 0489, La Tronche

41009

Local Institution - 0051, Seville

42601

Local Institution - 0516, Daegu

44093

Local Institution - 0009, Nantes

44195

Local Institution - 0083, Cleveland

46026

Local Institution - 0027, Valencia

48109

Local Institution - 0464, Ann Arbor

48149

Local Institution - 0046, Münster

49100

Local Institution - 0427, Petah Tikva

49241

Local Institution - 0517, Busan

49525

Local Institution - 0455, Grand Rapids

50139

Local Institution - 0373, Florence

50924

Local Institution - 0273, Cologne

55131

Local Institution - 0420, Mainz

55905

Local Institution - 0431, Rochester

56124

Local Institution - 0171, Pisa

61231

Local Institution - 0013, Bad Nauheim

63110

Local Institution - 0461, St Louis

69120

Local Institution - 0077, Heidelberg

69500

Local Institution - 0067, Bron

75013

Local Institution - 0004, Paris

75015

Local Institution - 0006, Paris

75093

Local Institution - 0492, Plano

75246

Local Institution - 0089, Dallas

75390

Local Institution - 0365, Dallas

76100

Local Institution - 0054, Rehovot

79106

Local Institution - 0071, Freiburg im Breisgau

80636

Local Institution - 0454, München

81377

Local Institution - 0022, München

85054

Local Institution - 0458, Phoenix

89081

Local Institution - 0404, Ulm

90000

Local Institution - 0025, Jerusalem

93053

Local Institution - 0440, Regensburg

100083

Local Institution - 0535, Beijing

100730

Local Institution - 0534, Beijing

Local Institution - 0502, Beijing

102218

Local Institution - 0553, Beijing

110016

Local Institution - 0501, Shenyang

Local Institution - 0538, Shenyang

116011

Local Institution - 0540, Dalian

130041

Local Institution - 0544, Changchun

160012

Local Institution - 0483, Chandigarh

200127

Local Institution - 0537, Shanghai

215006

Local Institution - 0545, Suzhou

250021

Local Institution - 0546, Jinan

325000

Local Institution - 0536, Wenzhou

330008

Local Institution - 0550, Nanchang

380060

Local Institution - 0482, Ahmedabad

400016

Local Institution - 0503, Chongqing

Local Institution - 0541, Chongqing

410011

Local Institution - 0548, Changsha

430060

Local Institution - 0542, Wuhan

450003

Local Institution - 0549, Zhengzhou

510120

Local Institution - 0539, Guangzhou

510515

Local Institution - 0543, Guangzhou

560099

Local Institution - 0480, Bengaluru

610000

Local Institution - 0533, Chengdu

610015

Local Institution - 0552, Chengdu

682001

Local Institution - 0481, Kochi

710061

Local Institution - 0547, Xi'an

1138603

Local Institution - 0477, Bunkyo-ku

3109601

Local Institution - 0419, Haifa

5265601

Local Institution - 0074, Ramat Gan

6423906

Local Institution - 0037, Tel Aviv

7830604

Local Institution - 0026, Ashkelon

9103102

Local Institution - 0057, Jerusalem

35233-1900

Local Institution - 0082, Birmingham

92037-1337

Local Institution - 0409, La Jolla

90048-3311

Local Institution - 0010, Los Angeles

94143-2204

Local Institution - 0406, San Francisco

94305-2200

Local Institution - 0079, Stanford

32608-1134

Local Institution - 0468, Gainesville

33606-3603

Local Institution - 0281, Tampa

46202-1243

Local Institution - 0424, Indianapolis

52242-1009

Local Institution - 0070, Iowa City

66160-8500

Local Institution - 0410, Kansas City

40217-1363

Local Institution - 0484, Louisville

02114

Local Institution - 0479, Boston

02118-2908

Local Institution - 0500, Boston

48202-2608

Local Institution - 0064, Detroit

68198-2265

Local Institution - 0435, Omaha

07962

Local Institution - 0490, Morristown

11030-3816

Local Institution - 0449, Manhasset

10019-1147

Local Institution - 0486, New York

11790-3407

Local Institution - 0007, Stony Brook

28204-2826

Local Institution - 0094, Charlotte

17602-2250

Local Institution - 0444, Lancaster

15213-2536

Local Institution - 0081, Pittsburgh

38138-1727

Local Institution - 0207, Germantown

84132-0001

Local Institution - 0402, Salt Lake City

22908-0001

Local Institution - 0478, Charlottesville

23298-5024

Local Institution - 0095, Richmond

40170-130

Local Institution - 0413, Salvador

70710-140

Local Institution - 0438, Brasília

30220-140

Local Institution - 0488, Belo Horizonte

90560-030

Local Institution - 0447, Porto Alegre

90620-001

Local Institution - 0450, Porto Alegre

12916-542

Local Institution - 0430, Bragança Paulista

14026-900

Local Institution - 0422, Ribeirão Preto

05403-000

Local Institution - 0412, São Paulo

20551-030

Local Institution - 0446, Rio de Janeiro

22061-080

Local Institution - 0451, Rio de Janeiro

04012-180

Local Institution - 0418, São Paulo

T2N 1N4

Local Institution - 0381, Calgary

V6E 1M7

Local Institution - 0467, Vancouver

L8L 2X2

Local Institution - 0414, Hamilton

N6A 5A5

Local Institution - 0411, London

G1V 4G5

Local Institution - 0093, Québec

550 01

Local Institution - 0086, Broumov

128 21

Local Institution - 0052, Prague

140 21

Local Institution - 0033, Prague

656 91

Local Institution - 0188, Brno

DK-9000

Local Institution - 0045, Aalborg

06000

Local Institution - 0001, Nice

07747

Local Institution - 0016, Jena

122 001

Local Institution - 0330, Gūrgaon

00189

Local Institution - 0028, Roma

798-8510

Local Institution - 0370, Uwajima

672-8044

Local Institution - 0208, Himeji-Shi

920-8641

Local Institution - 0457, Kanazawa

227-8501

Local Institution - 0107, Yokohama

783-8505

Local Institution - 0119, Nankoku-shi

514-8507

Local Institution - 0453, Tsu

980-8574

Local Institution - 0456, Sendai

545-0051

Local Institution - 0452, Osaka

564-8565

Local Institution - 0315, Suita

569-8686

Local Institution - 0471, Takatsuki-Shi

431-3192

Local Institution - 0168, Hamamatsu

104-0044

Local Institution - 0505, Chuo-Ku

173-0003

Local Institution - 0224, Itabashi-Ku

135-0061

Local Institution - 0466, Koto-Ku

160-8582

Local Institution - 0314, Shinjuku-ku

162-8666

Local Institution - 0475, Shinjuku-ku

810-0001

Local Institution - 0521, Fukuoka

6525 GA

Local Institution - 0442, Nijmegen

6229 HX

Local Institution - 0434, Maastricht

1105 AZ

Local Institution - 0197, Amsterdam-Zuidoost

3015 GD

Local Institution - 0213, Rotterdam

3584 CX

Local Institution - 0061, Utrecht

0424

Local Institution - 0441, Oslo

31-202

Local Institution - 0042, Krakow

50-556

Local Institution - 0038, Wroclaw

50-981

Local Institution - 0091, Wroclaw

02-097

Local Institution - 0338, Warsaw

02-507

Local Institution - 0203, Warsaw

35-055

Local Institution - 0072, Rzeszów

40-555

Local Institution - 0017, Katowice

41-800

Local Institution - 0415, Zabrze

15-276

Local Institution - 0030, Bialystok

93-338

Local Institution - 0416, Lódz

91-347

Local Institution - 0059, Lodz

4835-044

Local Institution - 0044, Guimarães

2805-267

Local Institution - 0015, Almada

2410-197

Local Institution - 0433, Leiria

1500-650

Local Institution - 0023, Lisbon

1649-035

Local Institution - 0024, Lisbon

4434-502

Local Institution - 0014, Vila Nova de Gaia

03722

Local Institution - 0012, Seoul

03080

Local Institution - 0217, Seoul

05505

Local Institution - 0049, Seoul

07198

Local Institution - 0040, Palma de Mallorca

08907

Local Institution - 0299, L'Hospitalet de Llobregat

03010

Local Institution - 0087, Alicante

08035

Local Institution - 0018, Barcelona

08036

Local Institution - 0056, Barcelona

SW3 6NP

Local Institution - 0445, London

G51 4TF

Local Institution - 0073, Glasgow

B15 2TH

Local Institution - 0407, Birmingham

EC1A 7BE

Local Institution - 0472, London

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT05582395 - A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy | Biotech Hunter | Biotech Hunter