Sex Differences in the Dilatory Response of Compound 21

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

October 3, 2022

Primary Completion Date

February 23, 2023

Study Completion Date

February 23, 2023

Conditions
Sex Differences
Interventions
DRUG

Compound 21

Compound 21 + Ringer's is perfused at 10 doses increasing serially for 10 minutes each from 10\^-12 M to 10\^-3 M

DRUG

Compound 21 + losartan

Compound 21 + losartan (43 µM) is perfused at 10 doses increasing serially for 10 minutes each from 10\^-12 M to 10\^-3 M.

Trial Locations (1)

52242

University of Iowa, Iowa City

All Listed Sponsors
lead

Anna Stanhewicz, PhD

OTHER