NCT05575297View on ClinicalTrials.gov

A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

December 20, 2021

Primary Completion Date

May 3, 2022

Study Completion Date

May 9, 2022

Conditions

Drug Interaction

Interventions

DRUG

Methotrexate Sodium

Methotrexate oral administration alone

DRUG

Rifampicin Sodium

Co-administration of methotrexate and rifampicin

DRUG

Febuxostat Tablets

Co-administration of methotrexate and febuxostat

Trial Locations (1)

Unknown

Seoul National University Bundang Hospital, Seoul

All Listed Sponsors

lead

Seoul National University Hospital

OTHER

NCT05575297 - A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects | Biotech Hunter | Biotech Hunter