10,000
Participants
Start Date
December 15, 2022
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2029
LDCT lung cancer screen, immediately
"Participants will receive the following things in sequence~1. Non-smoker lung cancer prediction model among Taiwanese population by questionnaire~2. Check autoantibodies against p53, NY-ESO-1, CAGE, GBU4-5, HuD, MAGE A4 and SOX2 in the blood of recruited patients and detect 133 SNPs and 11 mitochondrial mutations which are highly correlated with never-smoking lung cancer in our preliminary data~3. Check total bilirubin, urinary heavy metals, serum tumor marker, including CEA, alpha-fetal protein, etc.~4. Check pulmonary function test and chest X ray~5. Arrenge chest CT right away, and detection, classification, prediction of lung cancer risk in CT using deep learning and radiomics~6. Optimization and validation of lung cancer risk and probability prediction model: prospective multicenter clinical study."
LDCT lung cancer screen, later
"Participants will receive the following things in sequence~1. Non-smoker lung cancer prediction model among Taiwanese population by questionnaire~2. Check autoantibodies against p53, NY-ESO-1, CAGE, GBU4-5, HuD, MAGE A4 and SOX2 in the blood of recruited patients and detect 133 SNPs and 11 mitochondrial mutations which are highly correlated with never-smoking lung cancer in our preliminary data~3. Check total bilirubin, urinary heavy metals, serum tumor marker, including CEA, alpha-fetal protein, etc.~4. Check pulmonary function test.~5. Arrange AI-asisted chest X-ray right away.~6. Arrange chest CT three years later, and detection, classification, prediction of lung cancer risk in CT using deep learning and radiomics~7. Optimization and validation of lung cancer risk and probability prediction model: prospective multicenter clinical study."
RECRUITING
Chung Shan Medical University Hospital, Taichung
RECRUITING
National Taiwan University Hospital, Taipei
RECRUITING
National Taiwan University Hospital Hsin-Chu Branch, Hsinchu
RECRUITING
Hualien Tzu Chi Hospital, Hualien City
NOT_YET_RECRUITING
E-Da Hospital, Kaohsiung City
RECRUITING
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City
NOT_YET_RECRUITING
Ministry of Health and Welfare Shuang-Ho Hospital, New Taipei City
Ministry of Health and Welfare, Taiwan
OTHER_GOV
Chung Shan Medical University
OTHER