NCT05571878View on ClinicalTrials.gov

Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents

NAActive, not recruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

September 1, 2021

Primary Completion Date

May 30, 2025

Study Completion Date

May 30, 2025

Conditions
Major Depressive DisorderDepression
Interventions
DRUG

Humalog

All participants will be given an intranasal insulin challenge (80 IU) to assess brain insulin signalling via MRI based assay

DRUG

Saline nasal spray

All participants will be given an intranasal saline placebo (0.8 mL) in order to establish baseline brain insulin signalling via MRI based assay

Trial Locations (1)

M6J 1H3

Centre for Addiction and Mental Health, Toronto

All Listed Sponsors
lead

Centre for Addiction and Mental Health

OTHER