Linezolid or Vancomycin Surgical Site Infection Prophylaxis

PHASE4RecruitingINTERVENTIONAL
Enrollment

1,160

Participants

Timeline

Start Date

November 30, 2024

Primary Completion Date

April 3, 2025

Study Completion Date

April 3, 2026

Conditions
Antibiotic ProphylaxisGeneral Surgery
Interventions
DRUG

Vancomycin Injection

Patients receive a dose of 30 mg/kg of vancomycin (2 hours infusion) starting 2.5 hours before the scheduled time of surgical incision as defined in the French guidelines.

DRUG

Linezolid Injection

Patients receive a dose of 1200 mg of linezolid (30 minutes infusion) 30 minutes before the scheduled time of surgical incision.

Trial Locations (1)

13015

RECRUITING

Anesthésie Réanimation - Hôpital Nord (AP-HM), Marseille

All Listed Sponsors
lead

Assistance Publique Hopitaux De Marseille

OTHER