Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

May 12, 2023

Primary Completion Date

November 30, 2027

Study Completion Date

November 30, 2028

Conditions
Post Menopausal Osteoporosis
Interventions
DIETARY_SUPPLEMENT

Mother-of-pearl

"The mother-of-pearl, derived from the inner shell of marine molluscs, is composed of calcium carbonate and organic compounds, some of which peptides are active on the bone.~The mineralization inducing activity of the molecules extracted from the mother-of-pearl has been shown in vitro. Mother-of-pearl extract also contains molecules that inhibit the resorption activity of osteoclasts. Mother-of-pearl compounds can thus slow bone remodelling as showed in an ovariectomy-induced osteoporosis model in rat, where mother-of-pearl supplementation showed a better effect on limitation of bone loss than calcium carbonate supplementation."

DIETARY_SUPPLEMENT

Calcium Carbonate

Calcium carbonate is a source of calcium.

Trial Locations (7)

75014

NOT_YET_RECRUITING

APHP - Hôpital Cochin, Paris

Unknown

NOT_YET_RECRUITING

Hôpital Gabriel Montpied, Clermont-Ferrand

NOT_YET_RECRUITING

Clinique Universitaire de Rhumatologie, Grenoble

NOT_YET_RECRUITING

CH Emile Roux, Le Puy-en-Velay

NOT_YET_RECRUITING

Hôpital Edouard Herriot, Lyon

NOT_YET_RECRUITING

CH Roanne, Roanne

RECRUITING

CHU Saint-Etienne, Saint-Etienne

All Listed Sponsors
collaborator

Ministry of Health, France

OTHER_GOV

lead

Centre Hospitalier Universitaire de Saint Etienne

OTHER