200
Participants
Start Date
May 12, 2023
Primary Completion Date
November 30, 2027
Study Completion Date
November 30, 2028
Mother-of-pearl
"The mother-of-pearl, derived from the inner shell of marine molluscs, is composed of calcium carbonate and organic compounds, some of which peptides are active on the bone.~The mineralization inducing activity of the molecules extracted from the mother-of-pearl has been shown in vitro. Mother-of-pearl extract also contains molecules that inhibit the resorption activity of osteoclasts. Mother-of-pearl compounds can thus slow bone remodelling as showed in an ovariectomy-induced osteoporosis model in rat, where mother-of-pearl supplementation showed a better effect on limitation of bone loss than calcium carbonate supplementation."
Calcium Carbonate
Calcium carbonate is a source of calcium.
NOT_YET_RECRUITING
APHP - Hôpital Cochin, Paris
NOT_YET_RECRUITING
Hôpital Gabriel Montpied, Clermont-Ferrand
NOT_YET_RECRUITING
Clinique Universitaire de Rhumatologie, Grenoble
NOT_YET_RECRUITING
CH Emile Roux, Le Puy-en-Velay
NOT_YET_RECRUITING
Hôpital Edouard Herriot, Lyon
NOT_YET_RECRUITING
CH Roanne, Roanne
RECRUITING
CHU Saint-Etienne, Saint-Etienne
Ministry of Health, France
OTHER_GOV
Centre Hospitalier Universitaire de Saint Etienne
OTHER