NCT05570812View on ClinicalTrials.gov

Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV

PHASE2RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

March 3, 2023

Primary Completion Date

June 30, 2027

Study Completion Date

January 31, 2028

Conditions
Major Depressive DisorderAnxiety DepressionHIV
Interventions
DRUG

Placebo

(4-week ramp, 4-week steady dosing)

DRUG

Pregnenolone

(4-week ramp, 4-week steady dosing)

Trial Locations (1)

02114

RECRUITING

Massachusetts General Hospital, Boston

Sponsors
All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

collaborator

Institute for Medical Research, Inc.

INDUSTRY

lead

Massachusetts General Hospital

OTHER