How do Alpha Oscillations Shape the Perception of Pain? - An EEG-based Neurofeedback Study

NACompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

October 1, 2022

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2023

Conditions
Experimental Pain in Healthy Human Subjects
Interventions
BEHAVIORAL

attention right training, ARTNF

In a first verum neurofeedback condition, participants will be instructed to focus attention on their right hand and the up-regulation of alpha oscillations in the right hemisphere relative to alpha oscillations in the left hemisphere will be incentivized through neurofeedback.

BEHAVIORAL

attention left training, ALTNF

In a second verum neurofeedback condition, participants will be instructed to focus attention on their left hand and the down-regulation of right relative to left alpha oscillations will be incentivized.

BEHAVIORAL

sham attention right training, ARTsham

During the first sham neurofeedback condition, participants will be instructed to focus attention on their right hand. However, the feedback signal will not mirror their brain activity. Instead, the feedback signal and the corresponding reward of the last matching verum condition completed by a previous participant, i.e., ARTNF for ARTsham, will be replayed (yoked feedback).

BEHAVIORAL

sham attention left training, ALTsham

During the second sham neurofeedback condition, participants will be instructed to focus attention on their left hand. However, the feedback signal will not mirror their brain activity. Instead, the feedback signal and the corresponding reward of the last matching verum condition completed by a previous participant, i.e., ALTNF for ALTsham, will be replayed (yoked feedback).

Trial Locations (1)

81675

Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich

Sponsors
All Listed Sponsors
collaborator

German Research Foundation

OTHER

collaborator

Studienstiftung des deutschen Volkes

UNKNOWN

lead

Technical University of Munich

OTHER