RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure

NARecruitingINTERVENTIONAL
Enrollment

2,504

Participants

Timeline

Start Date

April 12, 2023

Primary Completion Date

April 1, 2026

Study Completion Date

April 1, 2036

Conditions
Heart Failure
Interventions
DEVICE

Implantable Cardioverter-Defibrillator (ICD) or Cardiac Resynchronisation Therapy Defibrillator (CRTD)

An ICD is a device that is implanted under the skin under a local anesthetic. It has a battery/generator component and leads which are fixed into the heart chambers. It has the ability to detect dangerous heart rhythms if they occur, and deliver a shock to treat this to help prevent sudden cardiac death. A CRTD is a pacemaker with a defibrillator function.

Trial Locations (47)

HP11 2TT

RECRUITING

Wycombe Hospital, High Wycombe

PL6 8DH

RECRUITING

Derriford Hospital, Plymouth

BH7 7DW

RECRUITING

Royal Bournemouth Hospital, Bournemouth

DL3 6HX

RECRUITING

Durham & Darlington NHS Foundation Trust, Darlington

BN2 5BE

RECRUITING

Royal Sussex County Hospital, Brighton

SS16 5NL

RECRUITING

Essex Cardiothoracic Centre, Basildon

NR31 6LA

RECRUITING

James Paget University Hospitals NHS FT, Gorleston-on-Sea

PO6 3LY

RECRUITING

Portsmouth Hospitals University NHS Trust, Portsmouth

SO16 6YD

NOT_YET_RECRUITING

Southampton Clinical Trials Unit, Southampton

RECRUITING

University Hospital Southampton NHS Foundation Trust, Southampton

CT1 3NG

RECRUITING

Kent & Canterbury Hospital, Canterbury

ME16 9QQ

RECRUITING

Maidstone Hospital, Maidstone & Tunbridge Wells NHS Trust, Maidstone

FY3 8NR

RECRUITING

Blackpool Victoria Hospiatal, Blackpool

L14 3PE

RECRUITING

Liverpool Heart & Chest, Liverpool

LE3 9QP

RECRUITING

Glenfield Hospital, Leicester

EC1A 7BE

RECRUITING

St Bartholomew's Hospital, London

NW3 2QG

RECRUITING

Royal Free Hospital, London

SE1 9RT

RECRUITING

Guy's Hospital, London

SE5 9RS

RECRUITING

King's College Hospital, London

SW3 6NP

RECRUITING

Royal Brompton Hospital, London

Wq12 0HS

RECRUITING

Hammersmith Hospital, Imperial College Healthcare NHS Trust, London

SW17 0QT

RECRUITING

St George's Hospital, Tooting

BL9 7TD

RECRUITING

Fairfield General Hospital, Northern Care Alliance NHS FT, Manchester

NE7 7DN

RECRUITING

Newcastle Freeman Hospital, Newcastle

TS4 3BW

RECRUITING

The James Cook University Hospital, Middlesbrough

NE63 9JJ

ACTIVE_NOT_RECRUITING

Wansbeck General Hospital, Ashington

YO12 6QL

RECRUITING

Scarborough Hospital, Scarborough

NG5 1PB

RECRUITING

Nottingham City Hospital, Nottingham

OX3 9DU

RECRUITING

The John Radcliffe Hospital, Oxford

AB25 2ZN

RECRUITING

Aberdeen Royal Infirmary, Aberdeen

EH16 4SA

RECRUITING

Royal Infirmary of Edinburgh, Edinburgh

TA1 5DA

ACTIVE_NOT_RECRUITING

Musgrove Park Hospital, Taunton

S5 7AU

RECRUITING

Northern General Hospital, Sheffield

TS19 8PE

RECRUITING

University Hospital of North Tees, Hardwick

GU16 7UJ

RECRUITING

Frimley Park Hospital, Camberley

RH1 5RH

RECRUITING

Surrey & Sussex Healthcare NHS Trust, Redhill

CF14 4XW

RECRUITING

University Hospital of Wales, Cardiff

CV2 2DX

RECRUITING

University Hospital Coventry, Coventry

WV10 0QP

RECRUITING

New Cross Hospital, Wolverhampton

PO19 6SE

RECRUITING

St Richards Hospital, Chichester

LS1 3EX

RECRUITING

Leeds General Infirmary, Leeds

WF1 4DG

RECRUITING

Pinderfields Hospital, Wakefield

WR5 1DD

RECRUITING

Worcestershire Royal Hospital, Worcester

M23 9LT

RECRUITING

Wythenshaw Hospital, Manchester

HU16 5JQ

RECRUITING

Castle Hill Hospital, Hull

EX2 5DW

RECRUITING

Royal Devon & Exeter Hospital, Exeter

SA6 6NL

RECRUITING

Morriston Hospital, Swansea

All Listed Sponsors
collaborator

British Heart Foundation

OTHER

collaborator

University of Southampton

OTHER

lead

University Hospital Southampton NHS Foundation Trust

OTHER