300
Participants
Start Date
June 6, 2023
Primary Completion Date
August 31, 2025
Study Completion Date
August 31, 2028
Blood sample collection
"Enrolled patients will undergo sequential blood collection beginning prior to conditioning, then on the day of transplant (day 0), followed by days 7, 14, 21, 28, 56 (2 months) and 90 (3 months) post-transplant.~Bone marrow aspirates taken within this period as part of routine care will also be collected, these are typically performed around day 100 and whenever there is suspicion of disease recurrence.~The study will also collect an additional blood sample at the onset of treatment for aGvHD for those who receive systemic corticosteroids (PO or IV steroid equivalent to ≥0.5mg/kg prednisolone)."
Bone marrow aspirate
Bone marrow aspirates taken within this period as part of routine care will also be collected, these are typically performed around day 100 and whenever there is suspicion of disease recurrence.
RECRUITING
Manchester Royal Infirmary, Manchester
RECRUITING
Royal Manchester Children's Hospital, Manchester
RECRUITING
The Christie NHS Foundation Trust, Manchester
The Christie NHS Foundation Trust
OTHER
University of Manchester
OTHER