NCT05566665 - Nosocomial Infections in ECMO Patients | Biotech Hunter

Enrollment

200

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions

Acute Respiratory Distress SyndromeNosocomial InfectionExtracorporeal Membrane Oxygenation Complication

Interventions

DIAGNOSTIC_TEST

Collection of blood and bronchoalveolar samples to study Pharmacokinetics of ceftazidime/avibactam, meropenem/varbobactam, ceftolozane/tazobactam, or cefiderocol

"The antibiotic treatment with ceftazidime/avibactam, meropenem/vaborbactam, ceftolozane/tazobactam, or cefiderocol will follow the standard clinical practice.~The concentration of ceftazidime/avibactam, meropenem/vaborbactam, ceftolozane/tazobactam, or cefiderocol will be measured at specific timepoints in plasma samples and bronchoalveolar lavage samples, and a PK analysis and modeling will be carried out ."

Trial Locations (2)

20100

NOT_YET_RECRUITING

Fondazione IRCCS Ca'Granda - Ospedale Maggiore Policlinico, Milan

20122

RECRUITING

Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan