Ketamine Versus Magnesium as Analgesic Adjuvants in Pediatric Adenotonsillectomy

PHASE4CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

November 1, 2022

Primary Completion Date

June 1, 2023

Study Completion Date

July 4, 2023

Conditions
Post Operative Pain, Acute
Interventions
DRUG

Ketamine hydrochloride

"Ketamine hydrochloride will be made in a 20 ml syringe in a concentration of 1.25 mg/ml. Patients will receive IV ketamine hydrochloride in a dose of 0.5 mg/kg (equivalent to 0.4 ml/kg) over 10 min.~The coordinator of the study will prepare blinded syringes for each group, while the anesthetist who will be in charge of anesthetic management during the operation will be unaware of the study medication."

DRUG

Magnesium sulfate

"A 20 ml syringe will contain magnesium sulphate in a concentration 100 mg/ml (10%). Patients will receive 40 mg/kg of IV magnesium sulphate (equivalent to 0.4 ml/kg) over 10 min.~The coordinator of the study will prepare blinded syringes for each group, while the anesthetist who will be in charge of anesthetic management during the operation will be unaware of the study medication."

Trial Locations (1)

Unknown

Faculty of Medicine, Cairo University, Cairo

All Listed Sponsors
lead

Cairo University

OTHER