Perioperative Steroid Dosing on the APR in AIS

PHASE4RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

January 3, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
DRUG

Dexamethasone postoperative

"Patients randomized to the dexamethasone cohort will be administered 8 mg of dexamethasone with 3 additional (8mg doses) administered at 8-hour intervals following surgery for a total of 4 doses.~All patients will undergo a standardized post-operative pathway in the hospital following surgery that has been utilized for all AIS patients at our center since 2014."

DRUG

Standard of Care

"Patients in the control group will receive one 8mg dose of dexamethasone intraoperatively as per standard of care anesthesia protocols. No sham medication will be utilized for control subjects.~All patients will undergo a standardized post-operative pathway in the hospital following surgery that has been utilized for all AIS patients at our center since 2014."

Trial Locations (1)

30329

RECRUITING

Children Healthcare of Atlanta, Atlanta

All Listed Sponsors
lead

Emory University

OTHER