Taiwan Real-world LDCT Screening Behavior and Outcome Research for High Risk Subjects Based on Health Promotion Administration

RecruitingOBSERVATIONAL
Enrollment

6,618

Participants

Timeline

Start Date

December 15, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2028

Conditions
Lung CancerHigh-Risk CancerSmokingPollution; ExposureFamily Relations
Interventions
DIAGNOSTIC_TEST

Low dose computed tomography

"1. Participants belonging to modified Lung RADS category 1 and 2 at baseline screening will undergo the LDCT next year after the discussion with the physicians in charge.~2. Participants with nodules belonging to modified Lung RADS category 3 and 4, growing nodules, or new nodules found on follow-up LDCT scans will undergo repeat CT every 3 to 6 months or be referred for diagnostic workup depending on the size and characteristics of the nodules as the regular clinical practice.~3. Volume doubling time (VDT) will be performed in the special groups with Lung RADS category 3 or 4, but the nodules with solid components ≧ 6mm and \< 9mm. A repeat LDCT scan will be performed around 3 months after the baseline screening.~4. Check total bilirubin, urinary heavy metals,CRP, serum tumor marker, including CEA, alpha-fetal protein, etc.~5. Check pulmonary function test."

Trial Locations (7)

402

RECRUITING

Chung Shan Medical University, Taichung

970473

RECRUITING

Hualien Tzu Chi Hospital, Hualien City

Unknown

RECRUITING

National Taiwan University Hospital Hsin-Chu Branch, Hsinchu

NOT_YET_RECRUITING

E-Da Hospital, Kaohsiung City

RECRUITING

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City

NOT_YET_RECRUITING

Ministry of Health and Welfare Shuang-Ho Hospital, New Taipei City

RECRUITING

National Taiwan University Hospital, Taipei

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

Gee-Chen Chang

OTHER