60
Participants
Start Date
February 15, 2023
Primary Completion Date
November 30, 2024
Study Completion Date
November 30, 2025
PSMA-radioguided surgery
Approximately 15-24 hours prior to surgery, 400-600 Megabecquerel (MBq) of 99mTc-PSMA-I\&S will be intravenously administered to the patient at the Nuclear Medicine department. Following this injection patients will be allowed to return home, and then present for their 99mTechnetium (99mTc)-based PSMA-radioguided salvage surgery the next day.
ADT
Standard 6 months of ADT according to current clinical guidelines. ADT consists of one subcutaneous depot of 22,5mg triptorelin (Pamorelin), with 4 weeks bicalutamide 50mg per os from 2 weeks before till 2 weeks after the first Pamorelin administration.
RECRUITING
Antoni van Leeuwenhoek Hospital, Amsterdam
The Netherlands Cancer Institute
OTHER