Tracer-Guided Surgery for Recurrent Prostate Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 15, 2023

Primary Completion Date

November 30, 2024

Study Completion Date

November 30, 2025

Conditions
Prostate Cancer
Interventions
PROCEDURE

PSMA-radioguided surgery

Approximately 15-24 hours prior to surgery, 400-600 Megabecquerel (MBq) of 99mTc-PSMA-I\&S will be intravenously administered to the patient at the Nuclear Medicine department. Following this injection patients will be allowed to return home, and then present for their 99mTechnetium (99mTc)-based PSMA-radioguided salvage surgery the next day.

DRUG

ADT

Standard 6 months of ADT according to current clinical guidelines. ADT consists of one subcutaneous depot of 22,5mg triptorelin (Pamorelin), with 4 weeks bicalutamide 50mg per os from 2 weeks before till 2 weeks after the first Pamorelin administration.

Trial Locations (1)

1066CX

RECRUITING

Antoni van Leeuwenhoek Hospital, Amsterdam

All Listed Sponsors
lead

The Netherlands Cancer Institute

OTHER