NCT05545007 - Preoperative vs Postoperative Hypofractionated Radiosurgery for Patients With Large Brain Metastases | Biotech Hunter

Enrollment

146

Participants

Timeline

Start Date

January 31, 2023

Primary Completion Date

January 31, 2027

Study Completion Date

January 31, 2027

Conditions

Brain Metastases, Adult

Interventions

RADIATION

Hypofractionated Radiosurgery (HSRS)

HSRS converges multiple radiation beams to deliver a single, large dose of radiation to a discrete tumor target with high precision, thereby minimizing radiation dose to the surrounding normal tissue.

PROCEDURE

Brain metastases surgical resection

Complete surgical resection of brain lesions with adeguate margins.

Trial Locations (9)

20089

RECRUITING

IRCCS Istituto Clinico Humanitas, Rozzano

20133

RECRUITING

Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan

25123

RECRUITING

ASST Spedali Civili di Brescia, Brescia

50134

RECRUITING

AOUC Azienda Ospedaliero-Universitaria Careggi, Florence

80147

RECRUITING

Ospedale del Mare, Naples

00161

NOT_YET_RECRUITING

Policlinico Umberto I, Rome

00168

NOT_YET_RECRUITING

Fondazione Policlinico Universitario Agostino Gemelli, Rome

00189

RECRUITING

AOU Sant'Andrea, Rome

05100

RECRUITING

Azienda Ospedaliera Santa Maria di Terni, Terni