NCT05538234View on ClinicalTrials.gov

Biomarkers of Kidney Function in Transplant Medicine

RecruitingOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

March 31, 2026

Conditions
Acute Kidney Injury
Interventions
DIAGNOSTIC_TEST

Laboratory values - baseline

Baseline laboratory values will be obtained

OTHER

Medical information 12 hours before organ harvesting

"* average hourly diuresis~* hypotension MAP\<65 Torr longer than 30 minutes (YES/NO)~* Furosemide administration (YES/NO)~* Mannitol administration (YES/NO)~* administration of anti-diuretic hormone (YES/NO)~* administration of vasopressors (YES/NO)~* polyuria \>3ml/kg/h (YES/NO)~* nephrotoxic agents during hospitalization (YES/NO)"

DIAGNOSTIC_TEST

Laboratory values - 12 hours after reperfusion

Laboratory values will be obtained 12 hours after reperfusion

DIAGNOSTIC_TEST

Laboratory values - 48 hours after reperfusion

Laboratory values will be obtained 48 hours after reperfusion

DIAGNOSTIC_TEST

Laboratory values - 7 days after reperfusion

Laboratory values will be obtained 7 days after reperfusion

DIAGNOSTIC_TEST

Laboratory values - 90 days after reperfusion

Laboratory values will be obtained 90 days after reperfusion

OTHER

Medical information during organ harvesting/transplantation

"Medical information during organ harvesting/transplantation~* hypotension MAP 65 Torr \> 5 minutes (YES/NO)~* vasopressor support (YES/NO, duration in minutes)"

PROCEDURE

Organ harvesting

Organ harvesting for transplant

PROCEDURE

Organ transplantation

Transplantation of the harvested organ

Trial Locations (1)

70852

RECRUITING

University Hospital Ostrava, Ostrava

All Listed Sponsors
lead

University Hospital Ostrava

OTHER