Intravenous Dexamethasone Effectiveness in Post Caesarean Section Analgesia

NACompletedINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

February 10, 2020

Primary Completion Date

September 30, 2020

Study Completion Date

January 4, 2021

Conditions
Cesarean SectionDexamethasonePostoperative PainSpinal Anesthesia
Interventions
DRUG

Dexamethasone 4mg

all patients had standard non-invasive monitoring including an electrocardiogram, non invasive blood pressure and pulse oxymetry. An 18-gauge intravenous cannula was inserted into the nondominant arm or hand and 500 ml of a saline solution (0.9 %) was infused. The prevention of postoperative nausea and vomiting (PONV) was assured to all patients by administering 4 mg of IV Ondansetron. Spinal anesthesia was performed according to our department protocol: L4-L5 or L3-L4 intervertebral space puncture using a 25 gauges needle, with injection of 0.5% hyperbaric Bupivacaine mixture (dose depending on patient height) associated with 2.5 ug Sufentanil and 100 ug Morphine. Before surgical incision, patients received either an intravenous injection of 8 mg (2 ml) Dexamethasone (DG) or 2 ml of a Saline solution (PG).

DRUG

Placebo

patients received 2ml of intravenous saline solution

Trial Locations (1)

2046

Mongi Slim University Hospital, La Marsa

All Listed Sponsors
lead

Mongi Slim Hospital

OTHER

NCT05535036 - Intravenous Dexamethasone Effectiveness in Post Caesarean Section Analgesia | Biotech Hunter | Biotech Hunter