PIB for Post-operative Analgesia After Laparotomy : Determining the Optimum Dose

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

December 1, 2022

Primary Completion Date

July 31, 2025

Study Completion Date

December 31, 2025

Conditions
Acute Post Operative PainLaparotomyEpidural Analgesia
Interventions
DRUG

Programmed intermittent epidural bolus 5 ml

patients in this group will receive a programmed epidural intermittent bolus of 5 mL every 60 min. Patients will also be allowed patient controlled epidural boluses of 5 ml, every 30 min, as needed to treat pain \> 4/10

DRUG

Programmed intermittent epidural bolus 6 ml

patients in this group will receive a programmed epidural intermittent bolus of 6 mL every 60 min. Patients will also be allowed patient controlled epidural boluses of 5 ml, every 30 min, as needed to treat pain \> 4/10

DRUG

Programmed intermittent epidural bolus 7 ml

patients in this group will receive a programmed epidural intermittent bolus of 7 mL every 60 min. Patients will also be allowed patient controlled epidural boluses of 5 ml, every 30 min, as needed to treat pain \> 4/10

DRUG

Programmed intermittent epidural bolus 8 ml

patients in this group will receive a programmed epidural intermittent bolus of 8 mL every 60 min. Patients will also be allowed patient controlled epidural boluses of 5 ml, every 30 min, as needed to treat pain \> 4/10

DRUG

Programmed intermittent epidural bolus 9 ml

patients in this group will receive a programmed epidural intermittent bolus of 9 mL every 60 min. Patients will also be allowed patient controlled epidural boluses of 5 ml, every 30 min, as needed to treat pain \> 4/10

DRUG

Programmed intermittent epidural bolus 10 ml

patients in this group will receive a programmed epidural intermittent bolus of 10 mL every 60 min. Patients will also be allowed patient controlled epidural boluses of 5 ml, every 30 min, as needed to treat pain \> 4/10

Trial Locations (1)

H1T2m4

RECRUITING

Maisonneuve-Rosemont Hospital, Montreal

All Listed Sponsors
lead

Ciusss de L'Est de l'Île de Montréal

OTHER