65
Participants
Start Date
November 16, 2022
Primary Completion Date
May 31, 2029
Study Completion Date
September 30, 2029
Obinutuzumab
Participants will receive intravenous (IV) obinutuzumab pretreatment on Days 1 and 2 of Cycle 1 (Cycle length = 21 days)
Glofitamab
"Arm A: Participants will receive IV glofitamab on Days 8 and 15 of Cycle 1, then on Day 1 of Cycles 2 and 3~Arm B: Participants will receive IV glofitamab on Days 8 and 15 of Cycle 1, then on Day 1 of each cycle thereafter~(Cycle length = 21 days)"
Rituximab
Participants will receive IV rituximab on Days 5, 6, 7, and 8 of Cycles 2 and 3 (Cycle length = 21 days)
Ifosfamide
Participants will receive IV ifosfamide on Days 3, 4, and 5 of cycle 1 and on Days 5, 6, 7, and 8 of Cycles 2 and 3 (Cycle length = 21 days)
Carboplatin
Participants will receive IV carboplatin on Days 3, 4, and 5 of cycle 1 and on Days 5, 6, 7, and 8 of Cycles 2 and 3 (Cycle length = 21 days)
Etoposide
Participants will receive IV etoposide on Days 3, 4, and 5 of cycle 1 and on Days 5, 6, 7, and 8 of Cycles 2 and 3 (Cycle length = 21 days)
Tocilizumab
Participants will receive IV tocilizumab as needed to manage cytokine release syndrome (CRS) events
RECRUITING
Rigshospitalet, København Ø
RECRUITING
Queensland Children?s Hospital, South Brisbane
RECRUITING
Perth Children's Hospital, Nedlands
RECRUITING
MSKCC, New York
RECRUITING
Ospedaliera Ospedale Infantile Regina Margherita, Turin
RECRUITING
Johns Hopkins University, Baltimore
RECRUITING
Hospital Infantil Universitario Niño Jesus, Madrid
RECRUITING
Hôpital Pellegrin, Bordeaux
RECRUITING
Children's Hospital of Alabama, Birmingham
RECRUITING
Cincinnati Children's Hospital Medical Center, Cincinnati
RECRUITING
Universitaetsklinikum Muenster, Münster
RECRUITING
Childrens Mercy Hosp & Clinics, Kansas City
RECRUITING
UCSF Benioff Children's Hospital Oakland, Oakland
RECRUITING
Kaiser Permanente Oakland Medical Center, Oakland
RECRUITING
Gustave Roussy, Villejuif
RECRUITING
Kaiser Permanente - Santa Clara, Santa Clara
RECRUITING
Kaiser Permanente - Roseville, Roseville
RECRUITING
Sun Yet-sen University Cancer Center, Guangzhou
RECRUITING
Dana-Farber Cancer Institute, Boston
RECRUITING
Hospital Erasto Gaertner, Curitiba
RECRUITING
Graacc-Grupo de Apoio ao adolescente e a crianca com cancer, São Paulo
RECRUITING
IRCCS Ospedale Pediatrico Bambino Gesù, Rome
RECRUITING
Ponadregionalne Centrum Onkologii Dzieci?cej ,,Przyladek Nadziei?;Klinika Transplantacji Szpiku, Onkologii i Hematologii Dzieciecej we Wroclawiu, Wroclaw
RECRUITING
Seoul National University Hospital- Pediatric Site, Seoul
RECRUITING
Asan Medical Center, Seoul
RECRUITING
Hospital Universitari Vall d'Hebron, Barcelona
Hoffmann-La Roche
INDUSTRY