20,000
Participants
Start Date
September 1, 2022
Primary Completion Date
March 1, 2025
Study Completion Date
March 1, 2025
Antibiotic dosage practice
"Patient inclusion starts day one, cross-over of departments from treatment A (single-dose) to B (multiple-dose) or vice versa after one year and end of inclusion happens after 2 years.~All centers in Denmark use either Cloxacillin/Dicloxacillin, Cefuroxime or both drugs as standard prophylactic antibiotic practice for THA. In cases of cephalosporin allergy or general beta lactam allergy, the antibiotic clindamycin may be administered.~In this trial, patients will be administered the standard prophylactic antibiotic practice of either single-dose (A) or multiple-doses (B) of antibiotics administered at each respective cluster that respective year. Both practices of dose administration for antibiotic prophylaxis (i.e. single- or multiple-dose) follow current standards of treatment and are based on present clinical practice guidelines."
Adeas Private Hospital, Parken, Copenhagen Ø
Department of Orthopedic Surgery and Traumatology, Bispebjerg, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen NV
Capio Private Hospital, Gildhøj, Brøndby
Department of Orthopedic Surgery, Hvidovre, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre
Department of Orthopaedic Surgery, Herlev, Copenhagen University Hospital - Herlev and Gentofte, Herlev
Acure Private Hospital, Kongens Lyngby
Aleris Private Hospital, Søborg, Søborg
Department of Orthopaedic Surgery, Gentofte, Copenhagen University Hospital - Herlev and Gentofte, Hellerup
Department of Orthopedic Surgery, Hillerød, Copenhagen University Hospital - North Zealand, Hillerød
CPH Private Hospital, Farum
Department of Surgery, Copenhagen University Hospital - Bornholm, Rønne
Aleris Private Hospital, Ringsted, Ringsted
Department of Orthopedic Surgery, Copenhagen University Hospital - Holbæk, Holbæk
Department of Orthopedic Surgery, Zealand University Hospital, Køge, Køge
Department for Planned Orthopaedic Surgery, Næstved, Copenhagen University Hospital - Næstved, Slagelse and Ringsted, Næstved
Department of Orthopedic Surgery, Copenahegn University Hospital - Nykøbing F, Nykøbing Falster
Kollund Private Hospital, Kollund, Kruså
Department of Orthopedic Surgery, Esbjerg, Hospital of South West Jutland, Esbjerg
Department of Orthopedics, Lillebaelt Hospital, Vejle, Vejle
Mølholm Private Hospital, Vejle, Vejle
Department of Orthopedic Surgery, Grindsted, Hospital of South West Jutland, Grindsted
Department of Orthopedic Surgery, Gødstrup Regional Hospital, Herning
Capio Private Hospital, Aarhus, Aarhus C
Aleris Private Hospital, Aarhus, Aarhus
Deaprtment of Orthopaedic Surgery, Aarhus University Hospital, Aarhus
Center for Planned Surgery, Silkeborg Regional Hospital, Silkeborg
Department of Orthopedic Surgery, Horsens Regional Hospital, Denmark, Horsens
Deparmtent of Orthopedic Sugery, Viborg Regional Hospital, Viborg
Deparmtent of Orthopedic Surgery, Randers Regional Hospital, Randers
Capio Private Hospital, Aalborg, Aalborg
Department of Orthopedic Surgery, Aalborg, Aalborg University Hospital, Aalborg
Department of Orthopedic Surgery, Farsø, Aalborg University Hospital, Farsø
Department of Orthopedic Surgery, Frederikshavn, Aalborg University Hospital, Frederikshavn
Department of Orthopedic Surgery, Hospital of Southern Jutland, Aabenraa and Sønderborg, Aabenraa
Capio Private Hospital, Hellerup and Odense, Hellerup
Department of Orthopedic Surgery and Traumatology, Odense University Hospital and Svendborg Hospital, Odense
University of Copenhagen
OTHER
University Hospital Bispebjerg and Frederiksberg
OTHER
Odense University Hospital
OTHER
Aarhus University Hospital
OTHER
University of Aarhus
OTHER
Sygehus Lillebaelt
OTHER
Soren Overgaard
OTHER