NCT05530434View on ClinicalTrials.gov

Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity

NARecruitingINTERVENTIONAL
Enrollment

128

Participants

Timeline

Start Date

April 11, 2022

Primary Completion Date

March 30, 2025

Study Completion Date

April 30, 2025

Conditions
Respiratory FailureObesity
Interventions
OTHER

transpulmonary pressure guided positive end expiratory pressure

Positive end expiratory pressure will be titrated to achieve a transpulmonary pressure of 0-2 cm H2O

OTHER

standard positive end expiratory pressure

Positive end expiratory pressure will be set to a standard 5-8 cm H2O by the clinician for spontaneous breathing trials

Trial Locations (1)

39216

RECRUITING

University of Mississippi Medical Center, Jackson

All Listed Sponsors
lead

University of Mississippi Medical Center

OTHER