The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly

CompletedOBSERVATIONAL
Enrollment

15

Participants

Timeline

Start Date

September 5, 2022

Primary Completion Date

July 18, 2023

Study Completion Date

July 18, 2023

Conditions
HypertensionFrailtyOld Age; DementiaOrthostatic IntoleranceOrthostatic HypotensionCerebral Hypoperfusion
Interventions
DRUG

Antihypertensive Agents

Study participants receive antihypertensive drug treatment as part of regular care to induce systolic BP (SBP) reductions ≥10 mmHg within 6-8 weeks, while reaching a treatment target of ≤140 mmHg, and while preserving diastolic BP ≥70 mmHg.

Trial Locations (1)

6525 GA

Radboudumc, Nijmegen

All Listed Sponsors
lead

Radboud University Medical Center

OTHER