Uncovering the Etiologies of Non-immune Hydrops Fetalis

NAEnrolling by invitationINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

February 28, 2027

Study Completion Date

February 28, 2027

Conditions
Non-Immune Hydrops Fetalis
Interventions
DIAGNOSTIC_TEST

Whole genome sequencing

"The investigators will study the genes in a fetus' or child's DNA using a test called genome sequencing. Genes are the instructions passed from individuals to a child, and genes determine how bodies are built and grow. Some medical conditions are caused by differences in genes, and the genome sequencing test looks for changes in genes and other parts of a person's genetic sequence (the genome).~Genetic material will be extracted from bio-specimens. Genome sequencing for this study will be performed at the UCSF Genomic Medicine Laboratory at UCSF. When the genome sequencing results are available, the investigators will arrange an in person or telehealth meeting to explain the test results and what the results mean for the fetus, pregnancy, and family."

Trial Locations (1)

94143

University of California, San Francisco, San Francisco

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

University of California, San Diego

OTHER

collaborator

Albert Einstein College of Medicine

OTHER

collaborator

Johns Hopkins University

OTHER

collaborator

University of Pennsylvania

OTHER

collaborator

The Jackson Laboratory

OTHER

lead

University of California, San Francisco

OTHER