Effect of Remimazolam vs Sevoflurane Anesthesia on Incidence of Emergence Agitation and Complications in Children Undergoing Ophthalmic Surgery

NACompletedINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

August 23, 2022

Primary Completion Date

February 6, 2023

Study Completion Date

February 7, 2023

Conditions
Emergence AgitationRemimazolamSevofluranePediatric Ophthalmic SurgeryAnesthesia, General
Interventions
DRUG

Remimazolam

Anesthesia was induced with Remimazolam 0.4-0.8 mg/kg (about 1 minute) by intravenous injection until the loss of consciousness (LoC), followed by remimazolam 1-2 mg/kg/h until the end of surgery.

DRUG

Sevoflurane

Anesthesia was induced with 8 % Sevoflorane by sevoflurane volatilization tank until the loss of consciousness (LoC), followed by 2 %-3 % Sevoflorane until the end of surgery.

DRUG

Fentanyl

Anesthesia was induced with fentanyl 3-4 ug/kg by intravenous injection after the LoC.

DRUG

Cisatracurium Besylate

Anesthesia was induced with cisatracurium besilate 0.1 mg/kg by intravenous injection after the LoC. And the cisatracurium besilate 0.02 mg/kg is allowed to add as appropriate during the operation.

DRUG

Remifentanil

After the LoC, remifentanil 0.1\~0.3 ug/kg/min inject intravenously until the end of surgery.

Trial Locations (1)

Unknown

the Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang

All Listed Sponsors
lead

Second Affiliated Hospital of Nanchang University

OTHER