Methotrexate Combined With Immunotherapy During Radiotherapy for Solid Tumors

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 15, 2021

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2026

Conditions
Solid Tumors
Interventions
DRUG

Methotrexate tablets

Tablets with 5mg methotrexate are taken orally twice a week during the whole course of radiotherapy

DRUG

Anti-PD-1 monoclonal antibody

Anti-PD-1 monoclonal antibody 200mg is given intravenously every 3 weeks from the first day of radiotherapy until or after the end of treatment.

RADIATION

Radiotherapy

6~15MV X-ray, 2Gy/time, 5times/week. The duration of radiotherapy depends on the target lesion.

Trial Locations (1)

224000

Yancheng First People's Hospital, Yancheng

All Listed Sponsors
lead

Yancheng First People's Hospital

OTHER

NCT05522582 - Methotrexate Combined With Immunotherapy During Radiotherapy for Solid Tumors | Biotech Hunter | Biotech Hunter