Minocycline for Acute Ischemic Stroke Undergoing Endovascular Treatment Due to Basilar Artery Occlusion (MIST-B)

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

March 4, 2023

Primary Completion Date

March 11, 2025

Study Completion Date

June 4, 2025

Conditions
Ischemic Stroke, AcuteMinocyclineEndovascular TreatmentBasilar Artery Occlusion
Interventions
DRUG

Minocycline

200 mg minocycline orally or via feeding tube, followed by 100 mg every 12 hours times for a total of 5 days. If vomiting occurs within half an hour of the first dose, the clinician should assess the necessary of re-administering 100mg based on the severity of vomiting. Considering the risk of difficulty in feeding tube before EVT, minocycline administered within one hours after EVT is acceptable.

Trial Locations (1)

710032

Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an

All Listed Sponsors
collaborator

Xi'an No.3 Hospital

OTHER_GOV

collaborator

Xi'an Gaoxin Hospital

OTHER

collaborator

First People's Hospital of Xianyang

OTHER

collaborator

Xi'an XD Group Hospital

UNKNOWN

collaborator

Central Hospital of Gansu Province

UNKNOWN

lead

Xijing Hospital

OTHER