Percutaneous Continuous Irrigation Combined With Transgastric Necrosectomy usingLAMS in Treatment of SAP

CompletedOBSERVATIONAL
Enrollment

8

Participants

Timeline

Start Date

January 1, 2019

Primary Completion Date

May 9, 2022

Study Completion Date

August 14, 2022

Conditions
Severe Acute PancreatitisPancreatic Necrosis
Interventions
PROCEDURE

Percutaneous Continuous Irrigation assisted Vacuum Drainage Combined With Transgastric Necrosectomy

All patients with SAP were given contrast enhanced CT scan within 48 hours after admission to identify the location and range of the necrosis. If the patient's condition progressively worsened, a multifunctional irrigation-assisted vacuum drainage tube was placed by the CT-guided Seldinger technique in each of the necrosis cavity. Subsequently, transgastric necrosectomy were performed by one or two experienced endoscopist under conscious sedation. The procedure was repeated until all loosely adherent necrotic material were cleared and replaced by granulation tissue. Percutaneous irrigation was stopped and replace with simple drainage if the patient's condition continues to improved and the cavity confirmed by CT was resolution. If the drainage volume was less than 10 mL/day for 3 consecutive days, clamp the drainage tube and remove it finally.

Trial Locations (1)

210008

Nanjing Drum Tower Hospital, Nanjing

All Listed Sponsors
lead

Chinese Medical Association

NETWORK

NCT05508828 - Percutaneous Continuous Irrigation Combined With Transgastric Necrosectomy usingLAMS in Treatment of SAP | Biotech Hunter | Biotech Hunter