Liberation From Mechanical Ventilation Using Extubation Advisor Decision Support

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

April 22, 2024

Primary Completion Date

July 31, 2025

Study Completion Date

October 31, 2025

Conditions
Airway Extubation
Interventions
DEVICE

Extubation Advisor

Participants undergoing a Spontaneous Breathing Trial (SBT) to assess readiness for extubation will be connected to a portable monitor displaying ECG, capnography, and other waveforms. This monitor will also be connected to a laptop containing the Extubation Advisor (EA) software. During the SBT, relevant patient information will be entered into the EA application and the EA application will record waveform data. When the SBT is complete, the EA application will analyze the waveform and patient data to generate a score summarizing the risk of extubation failure. A report will be generated and provided to the respiratory therapist and attending physician to help determine whether to proceed with extubation or not. The clinical outcome case report form will be completed at the time of hospital discharge.

Trial Locations (12)

T5H 3V9

RECRUITING

Royal Alexandra Hospital, Edmonton

R2H 2A6

NOT_YET_RECRUITING

St. Boniface Hospital, Winnipeg

R3A 1R9

NOT_YET_RECRUITING

Health Sciences Centre Winnipeg, Winnipeg

K7L 2V7

RECRUITING

Kingston Health Sciences Centre, Kingston

K1H 8L6

RECRUITING

The Ottawa Hospital, Ottawa

K2H 8P4

RECRUITING

Queensway Carleton Hospital, Ottawa

M4N 3M5

NOT_YET_RECRUITING

Sunnybrook Health Sciences Centre, Toronto

M5B 1W8

RECRUITING

Unity Health Toronto - St. Michael's Hospital, Toronto

G6V 3Z1

NOT_YET_RECRUITING

Hotel Dieu de Levis, Lévis

H2X 3E4

RECRUITING

Centre hospitalier de l'Université de Montréal (CHUM), Montreal

G1J 1Z4

NOT_YET_RECRUITING

Hopital de l'Enfant Jesus, Québec

G1V 4G5

NOT_YET_RECRUITING

Institut universitaire de cardiologie et de pneumologie de Québec, Ste-Foy

All Listed Sponsors
lead

Ottawa Hospital Research Institute

OTHER