Routine Versus Selective Intraoperative ECMO in Lung Transplant

NACompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

September 15, 2022

Primary Completion Date

March 15, 2023

Study Completion Date

December 15, 2023

Conditions
Lung Transplant; ComplicationsExtracorporeal Circulation; ComplicationsPostoperative Complications
Interventions
DEVICE

Routine ECMO

Routine ECMO during lung tansplant

DEVICE

On demand ECMO

"Selective, indication-based intraoperative cardiopulmonary support. In this group, the transplant will be planned without cardiopulmonary support. intraoperative ECMO will be used selectively based on hemodynamic and/or gas exchange abnormalities :~1. Inability to maintain adequate hemodynamics and stable perfusion or oxygenation during surgery~2. Prolonged high dose pressor required to maintain adequate perfusion~3. A sustained drop in cerebral saturation \> 25% of baseline despite initial attempts at optimization~4. Inability to tolerate pulmonary artery clamping~5. Inadequate gas exchange despite attempts at the optimization of ventilator parameters and treatments related to respiratory mechanics and ventilation/perfusion matching~6. Inadequate exposure to the surgical field"

Trial Locations (1)

H2X3E4

Centre Hospitalier de l'Université de Montréal, Montreal

All Listed Sponsors
lead

Centre hospitalier de l'Université de Montréal (CHUM)

OTHER