13
Participants
Start Date
August 26, 2022
Primary Completion Date
October 7, 2023
Study Completion Date
October 7, 2023
Low-intensity focused ultrasound pulsation (LIFUP)
LIFUP will be used to stimulate specific brain regions and assess their causal involvement in the control of conscious state and contents.
Functional Magnetic Resonance Imaging (fMRI) using Propofol
Propofol will be administered by intravenous infusion. All anesthesia equipment, supplies, and drugs will be provided by anesthesiologists from the University of Michigan Health System. The researchers will manually control the infusion of propofol to achieve target effect-site concentrations
University of Michigan, Ann Arbor
National Institute of General Medical Sciences (NIGMS)
NIH
University of Michigan
OTHER