Proper Duration of Suppressive Antibiotic Therapy After Debridement, Antibiotics, and Implant Retention

NARecruitingINTERVENTIONAL
Enrollment

438

Participants

Timeline

Start Date

December 31, 2024

Primary Completion Date

January 31, 2026

Study Completion Date

June 30, 2026

Conditions
Periprosthetic Joint InfectionAntibiotic Suppression
Interventions
DRUG

6 months of SAT

6 months of oral suppressive antibiotic therapy

DRUG

12 months of SAT

12 months of oral suppressive antibiotic therapy

DRUG

Indefinite SAT

Indefinite oral suppressive antibiotic therapy

Trial Locations (1)

21201

RECRUITING

University of Maryland, Baltimore

Sponsors
All Listed Sponsors
collaborator

OrthoCarolina Research Institute, Inc.

OTHER

collaborator

University of Arkansas

OTHER

collaborator

OrthoMichigan

UNKNOWN

collaborator

NYU School of Medicine

UNKNOWN

collaborator

Sinai Hospital

UNKNOWN

collaborator

MedStar Health

OTHER

lead

University of Maryland, Baltimore

OTHER

NCT05495815 - Proper Duration of Suppressive Antibiotic Therapy After Debridement, Antibiotics, and Implant Retention | Biotech Hunter | Biotech Hunter