Effect of Perioperative Gabapentin on Postoperative Opioid Requirements

PHASE4CompletedINTERVENTIONAL
Enrollment

114

Participants

Timeline

Start Date

July 27, 2021

Primary Completion Date

June 17, 2023

Study Completion Date

July 5, 2023

Conditions
Postoperative Pain
Interventions
DRUG

Preoperative Gabapentin/Postoperative Placebo

Postoperatively, this group will receive scheduled acetaminophen and ibuprofen every 6 hours, in addition to placebo every 12 hours. The placebo is encapsulated to appear identical to the active drug. This group will have oxycodone 5 mg every 6 hours as needed for pain.

DRUG

Preoperative Gabapentin/Postoperative Gabapentin

Postoperatively, this group will receive scheduled acetaminophen and ibuprofen every 6 hours, in addition to gabapentin every 12 hours. The gabapentin is encapsulated to appear identical to the placebo. This group will have oxycodone 5 mg every 6 hours as needed for pain.

Trial Locations (1)

46202

Indiana University School of Medicine, Indianapolis

All Listed Sponsors
lead

Indiana University

OTHER

NCT05494385 - Effect of Perioperative Gabapentin on Postoperative Opioid Requirements | Biotech Hunter | Biotech Hunter