Nigella Sativa for Selected Outcomes in Chronic Rhinosinusitis

NACompletedINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

August 7, 2022

Primary Completion Date

May 23, 2023

Study Completion Date

May 23, 2023

Conditions
Chronic Rhinosinusitis
Interventions
OTHER

Nigella sativa nasal oil drops

in addition to the standard treatment, the study group will receive one nasal drop of the prepared N. sativa nasal oil drops in each nostril twice daily which are equivalent to a daily dose of 100 milligram of a pure N. sativa oil for four weeks. N. sativa oil was prepared from N. sativa seeds and it was mixed in Sesame oil with a ratio of 1 to 1. The prepared drops will then be placed in dark containers with a specific dropper. Each participant will be instructed regarding the dose, proper position and steps, assisted by a flyer which will be developed by the researcher.

DRUG

standard treatment

intranasal corticosteroids in addition to nasal irrigation with sea water; for patients with allergy the standard treatment is oral antihistamines with or without oral corticosteroids.

Trial Locations (1)

Unknown

Cairo University, Cairo

All Listed Sponsors
lead

Cairo University

OTHER