30
Participants
Start Date
March 3, 2025
Primary Completion Date
May 31, 2027
Study Completion Date
November 30, 2027
Expiratory Muscle Strength Training
At visit 1, participants will be block randomized based on PWSS score (5-6 or 7+) to Expiratory Muscle Strength Training (EMST) for 6 to 8 weeks or no exercises. Participants in the EMST-150 group will perform 5 sets of 5 resistive expirations once a day with a 10-15 second rest between each repetition and a 1-2 minute rest between each set of 5 repetitions.
Maintenance Training
"At visit 2, participants with improved (decreased) CAPS-A hypernasality rating of 1 or more points, for whom the family and/or surgeon is not currently considering surgical intervention for VPI, will be further randomized to continue maintenance EMST exercises or no exercises for 6 months. Participants in the maintenance group will complete 3-5 sessions exercise sessions each week (rather than daily training), with 2 sets of 5 resistive expirations (rather than 5 sets)"
RECRUITING
UPMC Children's Hospital of Pittsburgh, Pittsburgh
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Noel Jabbour
OTHER