Assessment for Implementation Methods in Sepsis

NARecruitingINTERVENTIONAL
Enrollment

10,000

Participants

Timeline

Start Date

July 15, 2022

Primary Completion Date

July 15, 2027

Study Completion Date

July 15, 2027

Conditions
Sepsis SevereSeptic Shock
Interventions
OTHER

Sepsis Bundle

Intervention initiated within 1 hour or 3 hours of presentation depending on the Arm: 1. Measure lactate level. 2. Obtain blood cultures before administering antibiotics. 3. Administer broad-spectrum antibiotics. 4. Begin rapid administration of 30ml/kg crystalloid for hypotension or lactate greater than or equal to 4mmol/L. 5. Apply vasopressor if hypotensive during or after fluid resuscitation to maintain a mean arterial pressure greater than or equal to 65 mm Hg.

Trial Locations (1)

02903

RECRUITING

Rhode Island Hospital, Providence

All Listed Sponsors
lead

Rhode Island Hospital

OTHER