A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

RecruitingOBSERVATIONAL
Enrollment

1,600

Participants

Timeline

Start Date

August 16, 2022

Primary Completion Date

August 17, 2029

Study Completion Date

August 17, 2029

Conditions
Obstructive Hypertrophic Cardiomyopathy
Interventions
DRUG

Mavacamten

As per product label

DRUG

Non-mavacamten symptomatic oHCM therapy

Including Beta-blocker (BB), non-dihydropyridine (non-DHP) calcium channel blocker (CCB) and/or disopyramide as per product label

Trial Locations (98)

1090

NOT_YET_RECRUITING

Local Institution - 0083, Vienna

3100

NOT_YET_RECRUITING

Local Institution - 0085, Sankt Pölten

4021

NOT_YET_RECRUITING

Local Institution - 0086, Linz

5280

NOT_YET_RECRUITING

Local Institution - 0082, Braunau am Inn

6020

NOT_YET_RECRUITING

Local Institution - 0088, Innsbruck

8036

NOT_YET_RECRUITING

Local Institution - 0087, Graz

9020

NOT_YET_RECRUITING

Local Institution - 0084, Klagenfurt

10019

RECRUITING

Mount Sinai West, New York

10029

RECRUITING

Mount Sinai Hospital, New York

10595

RECRUITING

WMCHealth Advanced Physician Services, Valhalla

10719

NOT_YET_RECRUITING

Local Institution - 0096, Berlin

11030

RECRUITING

Northwell Health, Manhasset

11576

RECRUITING

Saint Francis Hospital, Roslyn

13326

RECRUITING

Bassett Medical Center, Cooperstown

15212

RECRUITING

AHN Allegheny General Hospital, Pittsburgh

15213

RECRUITING

University Of Pittsburgh, Pittsburgh

16321

NOT_YET_RECRUITING

Local Institution - 0095, Bernau

17603

RECRUITING

Lancaster General Hospital, Lancaster

18015

RECRUITING

St. Luke's University Health Network, Bethlehem

18711

RECRUITING

Geisinger Health System, Wilkes-Barre

20010

RECRUITING

MedStar Washington Hospital Center, Washington D.C.

21201

RECRUITING

University Of Maryland, Ihv, Baltimore

21218

RECRUITING

MedStar Health Research Institute, Baltimore

22908

RECRUITING

The Rector and Visitors of the Univ of Virginia, Charlottesville

23298

RECRUITING

VCU Medical Center, Richmond

24014

RECRUITING

Carilion Clinic; Virginia Tech-Carilion School of Medicine, Roanoke

26506

RECRUITING

WVU Hospitals, Morgantown

27710

RECRUITING

Duke University Health System, Durham

28007

NOT_YET_RECRUITING

Local Institution - 0102, Madrid

28040

NOT_YET_RECRUITING

Local Institution - 0108, Madrid

28207

RECRUITING

Focus Clinical Research, Charlotte

28222

NOT_YET_RECRUITING

Local Institution - 0104, Majadahonda

29010

NOT_YET_RECRUITING

Local Institution - 0103, Málaga

29605

RECRUITING

Prisma Health - Upstate, Greenville

30120

NOT_YET_RECRUITING

Local Institution - 0105, El Palmar

32209

RECRUITING

Uf Health Jacksonville, Jacksonville

33011

NOT_YET_RECRUITING

Local Institution - 0106, Oviedo

37203

RECRUITING

Tristar Centennial Medical Ctr, Nashville

38801

RECRUITING

Cardiology Associates Research, Llc, Tupelo

44106

RECRUITING

University Hospitals Cleveland Medical Center, Cleveland

44195

RECRUITING

Cleveland Clinic, Cleveland

44800

NOT_YET_RECRUITING

Local Institution - 0093, Saint-Herblain

45219

RECRUITING

Christ Hospital Health Network, Cincinnati

46202

RECRUITING

Indiana. University, Indianapolis

46237

RECRUITING

Franciscan Physician Network-Indiana Heart Physicians, Indianapolis

48149

NOT_YET_RECRUITING

Local Institution - 0100, Münster

48322

RECRUITING

Henry Ford Health System, West Bloomfield

48377

RECRUITING

UC Denver, AMC, Aurora

49525

RECRUITING

Spectrum Health Medical Group, Grand Rapids

52242

RECRUITING

University of Iowa Hospitals & Clinics, Iowa City

53226

RECRUITING

Medical College of Wisconsin, Inc (PI Address), Milwaukee

53792

RECRUITING

University Of Wisconsin - Madison, Madison

55407

RECRUITING

Minneapolis Heart Institute Foundation, Minneapolis

59000

NOT_YET_RECRUITING

Local Institution - 0090, Lille

60637

RECRUITING

University of Chicago Dept of Medicine, Chicago

63110

RECRUITING

Washington University, St Louis

64111

RECRUITING

St. Luke's Mid-America Heart Institute, Kansas City

66160

RECRUITING

University Of Kansas Medical Center & Medical Pavilion, Kansas City

67500

RECRUITING

Centre Hospitalier Haguenau, Haguenau

68124

RECRUITING

CHI Health Reseach Center, Omaha

73430

NOT_YET_RECRUITING

Local Institution - 0098, Aalen

75093

RECRUITING

Baylor Scott & White The Heart Hospital Plano, Plano

75208

RECRUITING

North Texas Cardiology Center, Dallas

75246

RECRUITING

Baylor Scott & White Research Institute, Dallas

76508

RECRUITING

Baylor Scott & White Medical Centre - Temple, Temple

77030

RECRUITING

The Methodist Hospital, Methodist Cancer Cencer, Houston

77084

RECRUITING

BI Research Center, Houston

80054

NOT_YET_RECRUITING

Local Institution - 0091, Amiens

83000

NOT_YET_RECRUITING

Local Institution - 0094, Toulon

85704

RECRUITING

Pima Heart and Vascular, Tucson

86000

NOT_YET_RECRUITING

Local Institution - 0089, Poitiers

90033

RECRUITING

Keck School of Medicine of USC-Usc, Los Angeles

91054

NOT_YET_RECRUITING

Local Institution - 0101, Erlangen

92037

RECRUITING

UC San Diego School of Medicine, La Jolla

94117

RECRUITING

University Of California San Francisco Medical Center, San Francisco

94304

RECRUITING

Stanford Health Care Hospital & Clinics, Palo Alto

96813

RECRUITING

University of Hawaii Cancer Center, Honolulu

98101

RECRUITING

Virginia Mason Medical Center, Seattle

99508

RECRUITING

Alaska Heart Institute, Anchorage

72205-7199

RECRUITING

UAMS, Little Rock

06106

RECRUITING

Hartford HealthCare, Hartford

02114

RECRUITING

Harvard (Massachusetts General Hospital), Boston

02215

RECRUITING

Harvard Medical School - Brigham and Women's Hospital (BWH), Boston

07601

RECRUITING

Hackensack University Medical Center, Hackensack

07960

RECRUITING

Morristown Medical Center, Morristown

37205-2018

RECRUITING

Saint Thomas Health, Nashville

01099

NOT_YET_RECRUITING

Local Institution - 0099, Dresden

04103

NOT_YET_RECRUITING

Local Institution - 0097, Leipzig

00717-1322

RECRUITING

Research & Cardiovascular Corp, Ponce

07198

NOT_YET_RECRUITING

Local Institution - 0109, Palma de Mallorca

09006

NOT_YET_RECRUITING

Local Institution - 0107, Burgos

SW3 6NP

NOT_YET_RECRUITING

Local Institution - 0113, London

W6 8RF

NOT_YET_RECRUITING

Local Institution - 0115, London

M13 9WL

NOT_YET_RECRUITING

Local Institution - 0112, Manchester

L14 3PE

NOT_YET_RECRUITING

Local Institution - 0111, Liverpool

B15 2GW

NOT_YET_RECRUITING

Local Institution - 0110, Birmingham

LS1 3EX

NOT_YET_RECRUITING

Local Institution - 0114, Leeds

CF14 4XW

NOT_YET_RECRUITING

Local Institution - 0116, Cardiff

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT05489705 - A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM) | Biotech Hunter | Biotech Hunter