Role of Echocardiography in Guiding Fluid Therapy in Shocked Patients With Impaired Cardiac Contractility in Emergency Department

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

August 1, 2021

Primary Completion Date

July 30, 2022

Study Completion Date

August 3, 2022

Conditions
Shock
Interventions
DIAGNOSTIC_TEST

passive leg raising test and fluid challenge

"Shocked patients were subjected to echocardiographic examination if (EF \<52%) .baseline LVOT VTI was obtained Then IVC scanning was done through subcostal Window and using M-mode the minimum and the maximum diameters were measured then the collapsibility index was calculated~Then passive leg raising test was done Patients who tolerated the PLR test and did not develop clinical or lung ultrasound signs of fluid overload (lung congestion) were given IV fluid bolus (250 ml normal saline) over 10 minutes followed by measurement of LVOT VTI.~Patients who did not tolerate PLR test or developed clinical or lung ultrasound signs of fluid overload (lung congestion) during PLR test were excluded from the third step (fluid challenge).~The differentiating factor used to allocate patient in which group (non-responder or responder) was LVOT VTI variability after fluid challenge (our gold standard to assess fluid responsiveness)."

Trial Locations (1)

Unknown

Faculty of Medicine, Alexandria

All Listed Sponsors
lead

Alexandria University

OTHER

NCT05488730 - Role of Echocardiography in Guiding Fluid Therapy in Shocked Patients With Impaired Cardiac Contractility in Emergency Department | Biotech Hunter | Biotech Hunter