Daily Chlorexidine Bath for Health Care Associated Infection Prevention

PHASE3CompletedINTERVENTIONAL
Enrollment

15,730

Participants

Timeline

Start Date

August 3, 2022

Primary Completion Date

March 31, 2024

Study Completion Date

March 31, 2024

Conditions
Health Care Associated InfectionVentilator Associated PneumoniaCentral Line-associated Bloodstream Infection (CLABSI)Catheter-Associated Urinary Tract Infection
Interventions
OTHER

2% chlorhexidine digluconate solution with surface-active agents

Bathing will be performed at least daily using 2% chlorhexidine digluconate solution with surface-active agents on all applicable bathing surfaces, which consists of the entire body surface of the patient except eyes, inner ear, oral mucosa, and areas of loss of skin continuity (such as burnt areas, pressure injuries, etc.); These areas will be bathed according to each center current practice.

OTHER

Usual Baths

Bathing will be performed at least daily using soap and water (performed according to the current practice in each center) on all applicable bathing surfaces, which consists of the entire body surface of the patient except eyes, inner ear, oral mucosa, and areas of loss of skin continuity (such as burnt areas, pressure injuries, etc.); These areas will be bathed according to each center current practice.

Trial Locations (16)

Unknown

Hospital Maternidade São José - UNESC - Fundação Social Rural de Colatina, Colatina

Hospital da Bahia, Salvador

Hospital da Cidade, Salvador

Hospital Universitário de Brasília, Brasília

Hospital Municipal de Maringá, Maringá

Hospital Regional do Baixo Amazonas Dr. Waldemar Penna, Santarém

Hospital das Clínicas da Universidade Federal de Pernambuco, Recife

Hospital Geral de Caxias do Sul, Caxias do Sul

Hospital Santa Cruz, Santa Cruz do Sul

Hospital Nereu Ramos, Florianópolis

Instituto Baía Sul de Ensino e Pesquisa Irineu May Brodbeck, Florianópolis

Hospital São Lucas, Aracaju

Hospital Aviccena, São Paulo

Hospital Naval Marcílio Dias, Rio de Janeiro

AC Camargo Câncer Center, São Paulo

BP-A Beneficiência Portuguesa de São Paulo, São Paulo

All Listed Sponsors
collaborator

Hospital Sírio-Libanês

UNKNOWN

collaborator

Hospital Israelita Albert Einstein

OTHER

collaborator

Hospital Moinhos de Vento

OTHER

collaborator

Hospital Alemão Oswaldo Cruz

OTHER

collaborator

A Beneficência Portuguesa de São Paulo

UNKNOWN

lead

Hospital do Coracao

OTHER