Central Sodium Sensing: Implications for Blood Pressure Regulation

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

January 31, 2025

Study Completion Date

January 31, 2025

Conditions
Salt Sensitivity of Blood Pressure
Interventions
OTHER

Dietary Intervention

Subjects will consume a low salt diet for 1 week and a high salt diet for 1 week to determine sodium sensitivity

OTHER

Hypertonic Saline

Subjects will undergo MRI with a hypertonic saline infusion with and without NKCC2 antagonism (furosemide)

Trial Locations (1)

19713

RECRUITING

William B Farquhar, Newark

All Listed Sponsors
lead

University of Delaware

OTHER