Vitamin D Supplementation on Surrogate Markers of Atherosclerosis

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

September 1, 2023

Primary Completion Date

June 30, 2026

Study Completion Date

August 30, 2026

Conditions
Atherosclerosis
Interventions
OTHER

Vitamin D supplementation

Appropriate diet and physical activity counselling to both groups. Supplementation with Vitamin D and oral Calcium-Doses of cholecalciferol (commercial name, Calcirol) 60,000 IU (sachets, dissolved in half glass milk) once per week for eight weeks for the intervention group and placebo (Lactose granules) to the placebo group according to the random numbers generated by the computer. After every 24 weeks blood 25 (OH) D levels will be assessed. If the subjects are found to be still deficient then supplementation of cholecalciferol 60,000 IU per week for eight weeks will be repeated.If the 25 (OH) D levels are normal, then cholecalciferol supplementation in doses of 200 IU per day will be given as a maintenance dose. Equal doses of calcium carbonate (1gm per day, commercial name Calcal) will be given to both the groups.

All Listed Sponsors
lead

Diabetes Foundation, India

OTHER

NCT05478291 - Vitamin D Supplementation on Surrogate Markers of Atherosclerosis | Biotech Hunter | Biotech Hunter