NCT05476432View on ClinicalTrials.gov

HAIC With One-day FOLFOX vs. HAIC With Two-day FOLFOX for Unresectable HCC: a Non-inferiority Study

PHASE3RecruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

July 26, 2022

Primary Completion Date

July 1, 2025

Study Completion Date

October 1, 2026

Conditions
Hepatocellular Carcinoma
Interventions
PROCEDURE

HAIC

The microcatheter was advanced into the hepatic artery, and patients were transferred to the inpatient ward for drug infusion via the hepatic artery

DRUG

FOLFOX 2d

Oxaliplatin, leucovorin, bolus fluorouracil, and infusional fluorouracil 2400 mg/m² over 46 hours

DRUG

FOLFOX 1d

Oxaliplatin, leucovorin, bolus fluorouracil, and infusional fluorouracil 2400 mg/m² over 23 hours

Trial Locations (3)

510060

RECRUITING

The First People's Hospital of Foshan, Foshan

RECRUITING

Cancer Center Sun Yat-sen University, Guangzhou

510620

RECRUITING

Guangzhou Twelfth People 's Hospita, Guangzhou

All Listed Sponsors
collaborator

Guangzhou No.12 People's Hospital

OTHER_GOV

collaborator

First People's Hospital of Foshan

OTHER

lead

Sun Yat-sen University

OTHER