NCT05475444View on ClinicalTrials.gov

PLGA Nanoparticles Entrapping Ciprofloxacin to Treat E-Fecalis Infections in Endodontics

NACompletedINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

March 1, 2020

Primary Completion Date

March 8, 2020

Study Completion Date

March 15, 2020

Conditions
Bacterial Infections Oral
Interventions
DEVICE

Chitosan Coated PLGA nanoparticles entrapping Ciprofloxacin incorporated in smart gels

antibacterial nanoparticles were used because of their small size, sustained release and positive charge which interact with the negatively charged surface of bacterial cell causing its destruction.

DEVICE

Ciprofloxacin paste and solution

Conventional antibacterial paste and solution were compared to nanoparticles smart gels to treat endodontics bacterial infection

Trial Locations (1)

11837

Mona Arafa, Cairo

All Listed Sponsors
lead

British University In Egypt

OTHER

NCT05475444 - PLGA Nanoparticles Entrapping Ciprofloxacin to Treat E-Fecalis Infections in Endodontics | Biotech Hunter | Biotech Hunter