Reducing Hypotensive Anesthesia Use with TXA During Orthognathic Surgery

PHASE4Enrolling by invitationINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 11, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Hypotension During SurgeryBlood Loss, Surgical
Interventions
OTHER

Avoidance of Deliberate Hypotensive Anesthesia

The anesthesia team will be asked to avoid deliberate hypotensive anesthesia and maintain blood pressure closer to the patient's baseline throughout the surgery.

DRUG

TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION

1g of tranexamic acid will be given intravenously to patient undergoing orthognathic surgery as routinely performed about 5-15 minutes before first surgical incision.

Trial Locations (1)

35205

UAB Hospital-Highlands, Birmingham

All Listed Sponsors
lead

University of Alabama at Birmingham

OTHER