Validation of a Prognostic Score for Steroid Therapy Response in Acute Severe Autoimmune Hepatitis

NANot yet recruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

June 1, 2024

Primary Completion Date

May 31, 2027

Study Completion Date

June 30, 2028

Conditions
Liver Failure, AcuteHepatitis, AutoimmuneOrgan Dysfunction ScoresRisk Factors
Interventions
OTHER

Corticosteroid therapy

Administration of high doses of corticosteroids as early as possible. Patient non-responder to treatment should lead to listing for emergency liver transplantation (LT).

Trial Locations (26)

13285

Hopital Saint Joseph, Service Hepato-gastro-enterologie, Marseille

14033

CHU de Caen, Hopital de la Cote de Nacre, Service Hepato-Gastro-Enterologie et Nutrition, Caen

21079

CHU Dijon, Service Hepato-gastroenterologie et cancerologie digestive, Dijon

25030

CHU Jean Minjoz Besançon, Service d'hepatologie et de soins intensifs digestifs, Besançon

29609

CHU Brest, Hopital de la Cavale Blanche Service Gastro-enterologie, Brest

31059

CHU Toulouse, Hopital Rangueil, Service Hepatologie, Toulouse

33604

CHU Bordeaux, GH Sud Haut-Leveque, Service Hepato-gastro-enterologie, Pessac

34295

CHU Montpellier, Hopital Saint Eloi, Service Hepato-gastro-enterologie, Montpellier

35000

CHU de Rennes, Hopital de Pontchaillou, Service Maladie du foie, Rennes

37170

CHU Trousseau Chambray, Service Gastro-enterologie et hepatologie, Chambray-lès-Tours

45100

CHU Orleans, Hopital de la Source, Service Gastro-enterologie et hepatologie, Orléans

49933

CHU Angers, Service Hepato-gastro-enterologie, Angers

51092

CHU Reims, Hopital Robert Debré, Service Hepato-Gastroenterologie et de Cancerologie digestive, Reims

59037

CHRU de Lille, Hopital Claude Huriez, Service des maladies de l'appareil digestif et de la nutrition, Lille

67200

CHU Strasbourg, Hopital de Hautepierre, Service Hepato-gastro-enterologie, Strasbourg

69003

CHU Hopital Edouard Herriot, Service Hepato-gastro-enterologie, Lyon

69317

CHU Lyon, Hopital Croix Rousse, Service Hepato-gastro-enterologie, Lyon

75012

AP-HP, Hopital St Antoine, Service Hepato-gastro-enterologie, Paris

75013

APHP, Hopital Pitie-Salpetriere, Service d'hepatologie et de gastroenterologie, Paris

75014

AP-HP, Hopital Cochin Service Hepatologie, Paris

76031

CHU Rouen, Service d'hepatogastro-enterologie, Rouen

86000

CHU La Miletrie, Service Hepato-gastro-enterologie, Poitiers

87042

CHU Limoges, Hopital Dupuytren, Service Hepato-gastroenterologie et nutrition, Limoges

93000

APHP, Hopital Avicenne, Service Hepatologie et Oncologie Hépatique, Bobigny

94800

AP-HP, Paul Brousse Hospital, Centre Hepato-Biliaire, Villejuif

06200

CHU Nice, Hopital de l'Archet 2, Service Hepatologie, Nice

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT05473403 - Validation of a Prognostic Score for Steroid Therapy Response in Acute Severe Autoimmune Hepatitis | Biotech Hunter | Biotech Hunter