NCT05469204View on ClinicalTrials.gov

Effect of Estrogen Treatment on Drug Metabolism and Transport

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

November 1, 2022

Primary Completion Date

January 30, 2026

Study Completion Date

June 30, 2026

Conditions
Transgender Persons
Interventions
DRUG

Midazolam oral solution

2 mg single-dose before and during estradiol treatment.

DRUG

Digoxin Oral Tablet

0.25 mg single-dose before and during estradiol treatment.

DRUG

Acetaminophen Oral Tablet

500 mg single-dose before and during estradiol treatment.

DRUG

Midazolam Injectable Solution

1 mg intravenous single-dose before and during estradiol treatment.

Trial Locations (1)

98195

University of Washington, Seattle

All Listed Sponsors
collaborator

National Institute of General Medical Sciences (NIGMS)

NIH

lead

University of Washington

OTHER