Cold Acclimation As a Modulator of Brown Adipose Tissue Function in Adults with Obesity

NAActive, not recruitingINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

July 25, 2022

Primary Completion Date

December 20, 2024

Study Completion Date

July 1, 2026

Conditions
Obesity
Interventions
OTHER

Cold acclimation

The cold water immersions will last 30-60 minutes per day and the volunteers will undergo 2-3 cold immersions per week.

OTHER

Intervention Control group - volunteers with obesity

Participants with obesity in the control group will undergo PET/CT scans at baseline and 12 weeks after the first scan.

OTHER

Acute cold exposure

All participants (lean and with obesity) will undergo PET/scans after 2 hours of cold exposure to investigate BAT perfusion and BAT glucose uptake.

Trial Locations (1)

20520

Turku PET Centre, Turku

All Listed Sponsors
collaborator

University of Turku

OTHER

collaborator

University of Barcelona

OTHER

collaborator

University of Ottawa

OTHER

lead

Turku University Hospital

OTHER_GOV