Didroxyprogesterone Promotes Natural Pregnancy in Infertile Patients With Endometriosis

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

December 10, 2022

Primary Completion Date

January 10, 2025

Study Completion Date

December 10, 2025

Conditions
Pregnancy Rate
Interventions
DRUG

didroxyprogesterone

Didroxyprogesterone group: the first menstrual cycle after operation began on the 14th to 27th day of each menstrual cycle. Didroxyprogesterone 10mg bid was given orally. It was planned to use 6 menstrual cycles (if the patient was naturally pregnant during the medication, the drug could be stopped), and guide the patient to try pregnancy. The observation period was 12 menstrual cycles after operation. Control group: no drugs were used after operation, and the patients were guided to try pregnancy. The observation period was 12 menstrual cycles after operation. Subjects need to complete up to 6 follow-up visits, including the first month after operation, the first menstrual cycle d7-13 after operation, the fourth menstrual cycle d7-13 after operation, the seventh menstrual cycle d7-13 after operation, the 13th menstrual cycle d7-13 after operation and 1-2 months after termination of pregnancy

All Listed Sponsors
collaborator

Guangdong Provincial People's Hospital

OTHER

collaborator

Shenzhen People's Hospital

OTHER

collaborator

First People's Hospital of Foshan

OTHER

lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

NCT05467852 - Didroxyprogesterone Promotes Natural Pregnancy in Infertile Patients With Endometriosis | Biotech Hunter | Biotech Hunter