The Flapless Approach in Periodontal Regeneration

NACompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

December 1, 2023

Study Completion Date

December 15, 2023

Conditions
Periodontitis, AdultIntrabony Periodontal Defect
Interventions
PROCEDURE

Flapless with Enamel Matrix Derivatives (EMD)

Experimental sites will receive a closed non-surgical treatment with a combined use of minicurettes and ultrasonic instruments with thin and delicate tips. Teeth will be instrumented until no residual calculus could be detected. A visualization of the root surface will be accomplished under magnification by using dental loups 4.0X. In the test group, the roots will be conditioned with 24% ethylenediaminetetraacetic acid (EDTA) for 2 minutes. After rinsing with sterile saline, enamel matrix derivatives (EMD) will be applied on the dried root surface.

PROCEDURE

Flapless without Enamel Matrix Derivatives (EMD)

Experimental sites will receive a closed non-surgical treatment with a combined use of minicurettes and ultrasonic instruments with thin and delicate tips. Teeth will be instrumented until no residual calculus could be detected. A visualization of the root surface will be accomplished under magnification by using dental loups 4.0X. No adjunct will be administered.

Trial Locations (1)

10126

CIR Dental School, Turin

All Listed Sponsors
lead

University of Turin, Italy

OTHER